Why Is DCI Important In PCOS?

Women with PCOS have been found to have significantly lowered levels of chiro-inositol, a component of the putative d-chiro inositol phosphoglycan mediator, in their muscle tissue. Those with insulin resistance have also been found to excrete chiro-inositol in urine six times quicker than normal women. In fact, researchers have now determined that DCI deficiency is the single strongest independent predictor and putative causative factor of insulin resistance. Studies with rats have shown that GK type II diabetic rats have a greatly reduced activity of the epimerase enzyme which converts myo-inositol into d-chiro inositol, as compared with Wistar control rats.

Normally people are able to produce their own DCI, but our poor PCOS-addled bodies just don’t seem to be able to get with the program when it comes to making this substance or keeping it around long enough to do it’s job!

Advertisements

Leave a Reply

Fill in your details below or click an icon to log in:

WordPress.com Logo

You are commenting using your WordPress.com account. Log Out / Change )

Twitter picture

You are commenting using your Twitter account. Log Out / Change )

Facebook photo

You are commenting using your Facebook account. Log Out / Change )

Google+ photo

You are commenting using your Google+ account. Log Out / Change )

Connecting to %s

%d bloggers like this: